How do I request larger quantities than those available on the website?

If you wish to request quantities that are greater than what is available, you will be asked to request a quote. Please contact customers@corebiogenesis.com 

Our team will then be in touch with more information regarding quantities available and pricing.

Who do I contact for product related questions?

If you wish to request information regarding the purchased product(s),  please fill out the contact form and one of our team members will get back to you shortly.

How is my personal data used?

Your personal data and order information will be stored in our internal systems. They will not be shared with third parties. You may request that we share with you the data associated with your account.

What are the available payment options?

Once you confirm an order request, payment will be done via bank transfer. Payment information will be outlined in the quote. We can also support you in case you prefer payment options via credit card.

What is the delivery time?

Depending on the country, standard delivery time is between 2 to 5 days.

How can I track my order?

When your order is confirmed, you will be sent a tracking number and a link to follow your order at all times.

What is the return policy?

If you receive a damaged product, we will replace it. However, no refund will be conducted. To notify our team of a damaged product, please fill out the contact form or contact directly your account manager and quality teams.

What does animal-free mean?

Our proprietary plant-based production technology allows us to manufacture recombinant growth factors that do not contain any animal-derived substances, and no other contaminating molecules like potential adventious agents typically encountered in products from mammalian origin.

How is the quality control for plant-derived recombinant growth factors?

Core Bio offers its customers effective, pure, and safe products. We carry out rigorous analysis of our products, including purity assessment to assure our customers high quality products. Our growth factors are tested for purity and biological activity. This information is provided in the certificate of analysis for each batch of every product.

How does FGF-2 TOP® compare to wild-type FGF-2 in terms of bioactivity and protein structure?

Core Bio FGF-2 TOP® is the 154 aa mature domain of FGF-2, tag-free with nine amino acid substitutions from the “wild type” version, which provides enhanced stability and protein bioactivity in cell culture conditions. FGF-2 TOP® significantly increases the functional half-life of FGF-2 from 10 h to greater than 20 days at 37 °C. Additionally, several studies shown FGF-2 TOP® being able to provide 10–100 times lower EC50 values and sustained in vitro FGFR-mediated activities due to increased thermal stability and lower heparin affinity in comparison to wild type FGF-2.

If I currently use FGF-2, how do I change my cell culture protocols to incorporate FGF-2 TOP®?

FGF-2 TOP® can be easily integrated into your current protocols to optimize your cell culture processes. You can make a direct molecule switch from wild-type FGF-2 to FGF-2 TOP® by simply starting to use this molecule at your working concentrations. This will enable to intensify your cell yields, obtain more homogeneous cell populations, while allowing to have weekend-free media feedings. Alternatively, if you are looking to improve your studies, develop a better performing protocol, and reducing the costs for the lab, you can explore different concentration titters and feeding schedules, allowing to use up to 50% less growth factor to grow FGF-2 dependent cell cultures.